There has been much speculation over the past year or so on the death of self-publishing, particularly for the comic book serial. Not surprising, as many self-publishers have either gone to established publishers (e.g. Linda Medley), gone to the Web (e.g. Phil & Kaja Foglio), or essentially given up (e.g. Mark Oakley).
I think that 2008 will be a make-or-break year. Three of the biggest names in self publishing have new projects starting up: Jeff Smith with RASL, Terry Moore with Echo, and the granddaddy of all Dave Sim with Glamourpuss.
The success of these three enterprises will tell us a lot about the viability of self-publishing comic books in the current era. Will their fans take to their new projects? And if so, will they buy the periodicals or wait for the inevitable trades? (Sim claims that the collection of Glamourpuss most likely won't come out until 2012 or thereabouts.)
However it goes, 2008 should make for an interesting year in comics publishing.